What is creatine and how does it work?

This video presents an overview of creatine along with a detailed explanation of the molecular mechanisms involved with it. It also demonstrates how creatine supplementation impacts the molecular mechanism to provide benefits such as increased strength, increased muscle mass, improved performance and fatigue resistance. Subscribe to the McMaster Demystifying Medicine YouTube channel: https://www.youtube.com/c/DemystifyingMedicine This video is provided for general and educational information only. Please consult your health care provider for Information about your health. Royalty-Free Music from Bensound This video was made by McMaster students Victor Nguyen, Ghazaleh Jafarazadeh-Maleki, Vaithiegaa Mathanarajan and Karan Taghizadeh in collaboration with the McMaster Demystifying Medicine Program. Copyright McMaster University 2020 References: Cooper, R., Naclerio, F., Allgrove, J., & Jimenez, A. (2012). Creatine supplementation with specific view to exercise/sports performance: an update. Journal of the International Society of Sports Nutrition, 9(1). https://doi.org/10.1186/1550-2783-9-33 Guimarães-Ferreira, L. (2014). Role of the phosphocreatine system on energetic homeostasis in skeletal and cardiac muscles. Einstein (São Paulo), 12(1), 126-131. https://doi.org/10.1590/s1679-45082014rb2741 de Souza e Silva, A., Pertille, A., Reis Barbosa, C., Aparecida de Oliveira Silva, J., de Jesus, D., & Ribeiro, A. et al. (2019). Effects of Creatine Supplementation on Renal Function: A Systematic Review and Meta-Analysis. Journal Of Renal Nutrition, 29(6), 480-489. https://doi.org/10.1053/j.jrn.2019.05.004