Researching the World’s Deadliest Infectious Disease – with Maximiliano Gutierrez

Join Max Gutierrez, Group Leader at the Crick, as he explains what happens to cells that are infected with tuberculosis and how his lab is studying our bodies’ response to this infection. *In this video* 0:00 Is TB still a problem today? 4:07 TB is the world's top infectious killer 6:59 What causes TB? 11:55 Genetics in action: how researchers study TB 28:03 Why TB treatment takes so long compared to other infections 34:57 Better TB treatments and drug combinations Tuberculosis is a devastating disease that has affected humans for centuries. Even today, it kills over a million people each year worldwide. TB is a curable disease but needs a six-month treatment period with at least three different antibiotics. The bacterium that causes tuberculosis, Mycobacterium tuberculosis, infects and lives within our own immune cells. By understanding how this bacterium survives and thrives inside these cells, Max’s lab hopes to find new approaches for treatments that help to eradicate this dangerous disease. *About Max Gutierrez* Max is the Group Leader of the Host-Pathogen Interactions in Tuberculosis Laboratory. He is a cell biologist originally from Mendoza, Argentina who has been a Principal Group Leader at the Crick since 2018. *About Crick Crash Courses* Crick Crash Courses started life as talks for our staff, to help everyone working here, scientists and non-scientists, better understand the Crick's discovery research into how life works. We have now opened our doors to our crash course talks, giving everyone, everywhere, the opportunity to hear directly from our scientists as they investigate some of the most complex challenges in human health. #Science # Tuberculosis #DiscoveryResearch *The Francis Crick Institute* The Francis Crick Institute is a biomedical research institute and independent charity. We bring together people from different fields and specialisms to tackle some of the biggest questions in health and disease. Based in the heart of London’s Kings Cross, we’re the biggest biomedical research facility under a single roof in Europe and are home to a free public exhibition space. *Keep up to date with everything going on at the Crick* • https://www.crick.ac.uk • https://bsky.app/profile/crick.ac.uk • https://linkedin.com/company/the-francis-crick-institute • https://www.instagram.com/thefranciscrickinstitute • https://www.tiktok.com/@thecrick • https://www.facebook.com/TheFrancisCrickInstitute