The First Generation That Won't Grow Old
You could be part of the first generation that won't grow old. This year, for the first time, doctors put a treatment into a living person's eye that is built to make old cells young again. So who gets there in time: your grandparents, your parents, you, or your kids? ✨ ☕ If you want superintelligence to benefit everyone, you can support this channel here: https://buymeacoffee.com/thegoodtakeoff ✨ 🎬 Want to learn how these films are made? I'll share everything I know soon: https://aistronauts.at/film-course We follow one number, how many months of life each year of research adds, and ask what it takes to push it to twelve: why bodies age, the four proteins that reset a cell, how AI speeds up the search, the first human eye, the skeptic's numbers, and why the finish line is a price tag we can decide on. Not medical advice. Every result in this film is described as what it is: a dish, a mouse, three patients, or a company's own figure. Every animation in this film was built from scratch for it, in code: no stock footage, no AI-generated images or video. Clips marked ORIGINAL FOOTAGE are real recordings, credited below. The narration uses a synthetic voice. Sources are listed below. Spotted an error? Tell us in the comments, corrections get pinned. CHAPTERS 0:00 The first generation that won't grow old 0:40 The number that decides the race 1:20 The number slipped 1:57 Why does a body grow old? 2:47 The reset button: four proteins 3:43 Artificial intelligence at the button 4:45 The first human eye 5:43 Next: the liver 6:29 One thread behind every disease 7:56 What the optimists estimate 8:28 Nobody has to lose 8:57 Four decisions that pulled prices down 9:53 Who gets there in time Which generation in your family do you think makes it? Tell us in the comments. ORIGINAL FOOTAGE • Jacob Kimmel and Blake Byers, Co-Founders, NewLimit · "2026 NewLimit Progress Update" (July 2026): https://www.youtube.com/watch?v=Gr11TITvLDM • S. Jay Olshansky, demographer, University of Illinois Chicago · The Dan Buettner Podcast, "The 90-Year Limit" (March 2026): https://www.youtube.com/watch?v=5SENvwmsCQc SOURCES The number • Our World in Data, the rise of maximum life expectancy: https://ourworldindata.org/the-rise-of-maximum-life-expectancy • Olshansky et al., Nature Aging 2024 (UIC): https://today.uic.edu/despite-medical-advances-life-expectancy-gains-are-slowing/ Why we age, and the reset button • Abad et al., reprogramming in living mice (2013): https://ecancer.org/en/news/4402-study-reports-first-ever-in-vivo-production-of-stem-cells • Lu et al., restoring vision in mice (Harvard, 2020): https://news.harvard.edu/gazette/story/2020/12/reversing-glaucoma-damage-and-vision-loss/ • University of Bonn, rejuvenated human cells (2026): https://uni-bonn.de/en/news/211-2026 Artificial intelligence at the button • OpenAI and Retro Biosciences, GPT-4b micro: https://openai.com/index/accelerating-life-sciences-research-with-retro-biosciences/ • NewLimit progress update (company figures): https://blog.newlimit.com/p/2026-may-june-progress-update The first human eye • FDA clears first human trial of epigenetic rejuvenation: https://www.biopharmatrend.com/news/fda-greenlights-first-human-trial-of-epigenetic-rejuvenation-therapy-for-vision-loss-1483/ • Life Biosciences, first-in-human ER-100 data (company): https://www.biospace.com/press-releases/life-biosciences-announces-first-in-human-data-from-ongoing-phase-1-trial-evaluating-er-100-in-optic-neuropathies • ClinicalTrials.gov, ER-100 Phase 1: https://clinicaltrials.gov/study/NCT07290244 One thread behind every disease • Demis Hassabis on 60 Minutes (CBS transcript): https://www.cbsnews.com/news/artificial-intelligence-google-deepmind-ceo-demis-hassabis-60-minutes-transcript/ • Barzilai, TAME trial: https://www.americangeriatrics.org/sites/default/files/inline-files/Thursday_Barzilai_.pdf The price tag • Lenmeldy at $4.25 million: https://www.biospace.com/orchard-sets-4-25m-us-price-for-gene-therapy-lenmeldy-on-heels-of-approval • Insulin patent sold for $1: https://insulin100.utoronto.ca/ • CMS Cell and Gene Therapy Access Model, 33 states: https://www.bioworld.com/articles/722166-cms-gene-therapy-access-model-goes-live-with-33-states-on-board • Medicines Patent Pool, 2025 annual report: https://medicinespatentpool.org/news-publications-post/from-innovation-to-access-mpps-2025-annual-report-highlights-strong-progress-partnership-value-and-growing-global-impact • Hepatitis C in Egypt, US$84 per course (BMC Medicine 2018): https://pmc.ncbi.nlm.nih.gov/articles/PMC6176525/
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