How to Lose Weight, Protect Muscle & Quiet Food Noise With Ozempic & GLP-1s | Dr. Elizabeth Kazarian

Most of the argument about GLP-1 medications is happening between people who have never had to get one approved. My guest today writes those prescriptions, fights those denials, and follows those patients for years, and her verdict is blunt: writing the prescription is the easiest part of the job. The hard part is a system in which the drug you get depends less on what works for you than on which manufacturer negotiated the better rebate. ▶ New full episodes every Monday – subscribe: https://www.youtube.com/@TheProofWithSimonHill?sub_confirmation=1 Visit The Proof website for the full show notes and supporting studies: https://theproof.com/podcast/ Simon's personal supplement stack: https://hub.theproof.com/supplements Elizabeth Kazarian is a physician double board-certified in Family Medicine and Obesity Medicine, practising in Washington DC. She has built an audience of more than 150,000 by translating clinical evidence into plain language and scrutinising the industries and policies that shape American health. In this episode we cover: - Why treating obesity means treating the brain, and what that means for willpower - The insurance machinery that decides which GLP-1 you are offered, and why - What actually happens when people stop taking these medications - Compounded GLP-1s: the access problem and the safety problem - BMI, body composition, and the tool she is forced to use - Menopause, PCOS, and fertility on and off these drugs - Why she argues family medicine is the original longevity medicine 00:00 Is Diet Soda Bad for You? Sweetener Myths Debunked 05:39 Wellness Influencers vs Real Medical Training 12:40 Obesity Stigma and the GLP-1 "Easy Way Out" Myth 21:54 Telehealth GLP-1s, Compounding Risks, and BMI Cutoffs 33:07 Tirzepatide vs Semaglutide: Which GLP-1 Gets Covered? 37:31 How Doctors Should Talk About Your BMI 47:00 GLP-1 Gatekeeping, Food Noise, and Alcohol Cravings 57:00 GLP-1 Dosing and Weight Regain After Stopping 01:02:43 Health Markers Over Goal Weight: 2026 Cholesterol Guidelines 01:10:57 How to Manage GLP-1 Nausea, Constipation, and Hydration 01:18:51 Do Peptides Work? Biohacking vs Real Longevity Medicine 01:27:17 PBMs, GoodRx, and Cost Plus Drugs Explained 01:34:10 Ozempic Babies, PCOS, and GLP-1 Fertility Effects 01:47:29 Pilates, Exercise, and Menopause Belly Fat 01:53:33 Is HRT Safe? Menopause Treatment vs Product Scams 02:03:19 Health Care Is Political: How to Fix US Healthcare You can follow Dr Elizabeth Kazarian's work on https://www.instagram.com/drkazarian/, where she shares evidence-based education on obesity medicine, GLP-1 therapies, and women's cardiometabolic health. Subscribe and stay connected: Found this episode valuable? Subscribe to The Proof on YouTube and hit the notification bell to stay updated. Listening on Spotify or Apple Podcasts? Follow the show to ensure you never miss an episode. Simon This episode is brought to you by: 38TERA 38TERA’s BDR is a clinically dosed gut health supplement for improved digestion, less bloating, better bowel movements and a healthier microbiome. Head to https://38tera.com/?ref=SIMON and use code THEPROOF for a discount at checkout. 38Tera ships to the United States, Australia, and New Zealand. Shokz Shokz OpenFit Pro brings Open-Ear Noise Reduction to open-ear listening, so background noise feels farther away while you stay connected to your surroundings. Head to https://beopen.shokz.com/THEPROOF and use code THEPROOF for a long-term discount on all Shokz products, stackable with other official promotions. SwimClub SwimClub is a science-backed supplement designed to support male fertility, sperm health, and reproductive wellness. Head to http://swimclub.co/theproof to get 25% off your first order with code THEPROOF. Function Health Make knowing your health part of your holiday plans. Function gives you access to 160+ lab tests for $365 a year—about a dollar a day. Join at http://functionhealth.com/SIMONHILL and use code SIMON25 for a $25 credit. Function Health ships to 48 U.S. states, excluding Rhode Island, Hawai‘i, and Puerto Rico. IM8 With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on http://im8health.com/. IM8 ships to 27 countries including the U.S., Canada, the U.K., Australia, and many regions across Europe, Asia, and South America. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on http://join.whoop.com/simon. Whoop ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia.