The Drug That Could Make Knee Replacement Obsolete

https://www.thesurgeonunmasked.com 🛠 Recovery products I recommend: https://www.thesurgeonunmasked.com/recovery-essentials — MEND and Polar Products are paid links (I earn a commission); everything else is a plain, non-affiliate link. I replace knees for a living — and a new drug in Phase 3 trials just posted knee arthritis results unlike anything I've seen from a medication. In the TRIUMPH-4 trial, patients on the highest dose lost nearly 29% of their body weight — about 71 pounds on average — knee pain scores fell by roughly three-quarters, and some patients reported no knee pain at all by the end. In this episode: what Ozempic, Wegovy, Mounjaro, and Zepbound already mean for joint replacement patients — BMI cutoffs, whether these drugs actually relieve arthritis pain, and what the early data shows about surgical outcomes. Plus the muscle-loss and nutrition problem nobody warns you about, when to stop these medications before anesthesia, and the four questions to ask your surgical team. Chapters: 0:00 A Drug That Could Change Knee Arthritis 1:02 GLP-1s and the BMI Barrier to Surgery 2:06 Do They Actually Help Knee Pain? 2:45 Retatrutide: The One to Watch 4:12 The Trade-Offs 4:39 If You Still Need a Knee Replacement 5:55 Muscle Loss, Nutrition & Bone 7:25 Should You Stop the Drug Before Surgery? 8:26 Four Questions to Ask Your Surgical Team 9:05 The Bottom Line THE SUPPLEMENT I MENTIONED These are affiliate links and I may earn a commission if you purchase through them. MEND Medical Food for Joint Replacement Support (the post-surgical nutrition supplement from this episode) — save 10% with code GETREADY10: https://mend.me/discount/GETREADY10?redirect=/products/medical-food-joint-replacement I earn a commission on MEND purchases made through my links or code. Disclosure: OrthoLoneStar has an ownership stake in MEND Nutrition. I am an owner and partner in Texas Orthopedics, which is a division of OrthoLoneStar. You can choose any product or retailer; your care does not depend on buying through me. ABOUT THE SURGEON UNMASKED I'm Dr. Randall Schultz, an orthopedic surgeon specializing in hip and knee replacement — and a knee replacement patient myself. This channel exists to demystify joint replacement so you feel less afraid and more prepared. Subscribe for new episodes: https://www.youtube.com/@TheSurgeonUnmasked DISCLAIMER This video is for education and general information only — it is not medical advice and does not create a doctor-patient relationship. Do not start, stop, or change any medication based on a YouTube video. Your surgeon, your anesthesiologist, and your prescribing physician should make those decisions together. #kneereplacement #ozempic #glp1 #kneearthritis #jointreplacement